![]() The usual total dose: 0.08 to 1 mg (mean: 0.65 mg).įlumazenil dose in s uspected benzodiazepine overdose: Limited data available:.may repeat 0.01 mg/kg (maximum dose: 0.2 mg) after 45 seconds, and then every minute to a maximum total cumulative dose of 0.05 mg/kg or 1 mg, whichever is lower.Initial dose: 0.01 mg/kg IV (maximum dose: 0.2 mg) given over 15 seconds.In the event of resedation, repeat doses may be given at 20-minute intervals if needed, at 0.5 mg per minute to a maximum of 1 mg total dose and 3 mg in 1 hour.įlumazenil dosage in children: Flumazenil dose in b enzodiazepine reversal when used in conscious sedation or general anesthesia:.If a patient has not responded 5 minutes after a cumulative dose of 5 mg, the major cause of sedation is not likely due to benzodiazepines or may be due to exposure to additional CNS depressants (eg, opioids).Additional titration up to a total dose of 5 mg can be done in patients with a partial response with a 3 mg dose (although doses >3 mg do not reliably produce additional effects).The maximum total cumulative dose of flumazenil: 5 mg IV over 30 seconds repeated at 1-minute intervals.if the desired level of consciousness is not obtained 30 seconds after the dose, 0.3 mg can be given over 30 seconds.Initial dose: 0.2 mg IV over 30 seconds. ![]() ![]() Repeat doses may be given at 20-minute intervals as needed at 0.2 mg per minute to a maximum of 1 mg total dose and 3 mg in 1 hour.įlumazenil dose in the m anagement of benzodiazepine overdose:.1 mg IV (usual total dose: 0.6 to 1 mg).If the desired level of consciousness is not obtained, 0.2 mg may be repeated at 1-minute intervals.Initial dose: 0.2 mg IV over 15 seconds.It is indicated for the treatment of benzodiazepine overdose.įlumazenil dosage in adults: Flumazenil dose in Benzodiazepine reversal when used in conscious sedation or general anesthesia:. ![]()
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